Larry King and Shawn King are calling it quits after almost 22 years of marriage.

King, 85, filed for divorce from his seventh wife on Tuesday, his lawyer confirmed to Page Six.

According to docs obtained by Page Six (via The Blast), King cited “irreconcilable differences” as the reason for the split and lists the date of separation as June 6, 2019.

It’s the second time the pair have separated. They previously filed for divorce in 2010 but eventually reconciled.

Shawn, 59, and Larry tied the knot in 1997 and share two sons together, 20-year-old Chance and 19-year-old Cannon.

The former CNN host has been married eight times, twice to the same woman.

In 2016, insiders told Page Six that Larry “swings back and forth on whether to file papers” after rumors that Shawn had been carrying on a yearlong affair with public-speaking guru Richard Greene.

Larry spoke out about the alleged affair at the time, saying, “I’ve been in the business now maybe 60 years and I’ve dealt with rumors long time. [I’ve] interviewed people involved with rumors, and rumors are what they are — rumors, and to tell you the truth, I don’t pay any attention to them.”

Rumors of the pair’s crumbling marriage continued into late 2017 when a source told us Larry has been “miserable for a decade.”

That same year, Larry rang in his 84th birthday without Shawn.