Kim Kardashian and Kanye West have worn out their welcome with so many at Paris fashion week, they’ve been branded by industry insiders tired of their antics as “fashion flu.”

The rapper and his reality-star wife have grabbed headlines in the City of Light this week by bringing their 1-year-old child North to a Balenciaga show, holding up Lanvin’s show for 40 minutes, getting punked by a Ukrainian prankster outside Balmain’s show, and even revealing their collective cleavage.

“People are so mad about Kimye being here,” sniffed a fashion insider, adding that Paris regulars are “fatigued with the whole family.” (Kim’s sister Kendall Jenner walked in Balmain’s Paris show, and momager Kris is also in town.)

Another insider was overheard on Thursday in Paris complaining that the ubiquitous Kim and Kanye have been a fashion headache. A pro shot back, “No, you mean a fashion [chronic fatigue].”

A source explained the frustration: “They hold up shows and they draw paparazzi wherever they go. They’re seen here as the ultimate try-hards. It was funny when they were a novelty.”

After the pair showed up late to Lanvin’s show — where Kim wore a skirt so short she used her hand as an accessory to cover her crotch in the front row — they were booed by photographers.

Kanye wore his own low-cut top, exposing ample “moobs.”

On Friday, some breathed a sigh of relief when the pair wasn’t at the vaunted Dior show with VIPs Carla Bruni, Marion Cotillard and Dakota Fanning. (However, little North has won hearts, and was being called “Lil’ Kimye” on the fashion circuit).

Meanwhile, Vogue editor Anna Wintour — who encouraged Kimye by putting them on her cover — was seen running out of the Dior show before it officially ended and designer Raf Simons could take his bow.

An Instagram post by W contributor Giovanna Battaglia showed Wintour wildly looking for the exit as models were still on the runway.

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She later showed up in Venice for George Clooney’s wedding to Amal Alamuddin.