After Kanye West blasted Annie Leibovitz at the Cannes Lions Festival (claiming she bailed as his wedding fotog days before the event), the ranting rapper was at it again Friday, lambasting fashion house Louis Vuitton and Nike for discrimination at London’s Wireless Festival.

West was performing as a fill-in for Drake, but in the middle of “Runaway,” he made a 15-minute speech railing at the fashion industry and drawing boos.

“I’m not going to diss Nike or anything, but don’t discriminate against me. They tell me, ‘Sit in the front row. Wear this jacket I made for you and do as you’re told.’ ”

West added, wearing a black mask: “I’m not dissing Louis Vuitton, I’m not dissing the Gucci group. I’m just saying, don’t discriminate against me because I’m a black man, or because I’m a celebrity, to determine that I can’t create … no black guy or celebrity is making no Louis Vuitton nothing. That’s why I wear this mask. [Bleep] my face!”