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Angelina dumped Brad after private eye uncovered Marion Cotillard affair

Angelina Jolie has filed for divorce from Brad Pitt after learning he was cheating on her with his sexy co-star, a well-placed source told The Post on Tuesday.

“She hired a private eye because she felt that he was fooling around with her on the set, and it turns out, he was. And that was the final straw,’’ the source said.

Pitt, 52, had been rumored to have been cozying up to his “Allied’’ co-star Marion Cotillard, 40, for months during the pair’s filming of the World War II drama in London.

The PI discovered that Pitt was cheating on his wife of two years with Cotillard — while also partying like a single guy on a mission, the source said.

“The atmosphere [off-set] was full of hard drugs and Russian hookers, and Angie was told Brad got caught up in it,’’ the source said.

“He’s in the throes of some insane midlife crisis, and Angie is fed up.”

But a source close to Cotillard denied the Pitt affair rumors and insisted she is still with her long-term partner, French actor and director Guillaume Canet.

“They are still very much together. They have been a couple since 2007 and have one child but have never married,’’ the source said of Cotillard and Canet.

The source could not confirm French reports that Cotillard is pregnant with her second child with Canet.

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MR. AND MRS. SMITH, Angelina Jolie, Brad Pitt, 2005, TM Copyright (c) 20th Century Fox Film Corp. All rights reserved.
That's hot: Brad Pitt and Angelina Jolie were rumored to first connect on the set of their hit movie "Mrs. and Mrs. Smith" in 2005.Everett Collection
WESTWOOD, CA - JUNE 07: (L-R) Regency Enterprises' David Matalon, actor Brad Pitt, Producer Arnon Milchan, actress Angelina Jolie and News Corp. President/Chief operating officer Peter Chernin arrive at the premiere of "Mr. & Mrs. Smith" at the Mann Village Theater on June 7, 2005 in Westwood, California. (Photo by Kevin Winter/Getty Images)
Jolie and Pitt make a point to stand separately at the Los Angeles premiere of "Mr. and Mrs. Smith" on June 7, 2005.Getty
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Angelina Jolie has given birth in Namibia to a baby girl called Shiloh Nouvel Jolie-Pitt This is the first child for Brad Pitt and Angelina Jolie - the couple already have two adopted children Maddox and Zahara. ++STOCK PICTURES TO GO WITH BIRTH STORY+++ Brad Pitt and Angelina Jolie finally make their romance public as they head out on his and hers motorcycles in Edmonton, Canada. The couple seemed very happy together as they headed to a local safeway supermarket and picked up supplies. As they left the store and headed back to their bikes Brad held Angelina's arm and the couple shared a joke. After loading up Jolie had some trouble getting her bike started but with a little help from Brad they were soon on their way home. Picture by: Tom Vickers/ Westley Hargrave Ref: TVWH 250905 A EXCLUSIVE Splash News and Pictures Los Angeles: 310-821-2666 New York: 212-619-2666 London: 207-107-2666 photodesk@splashnews.com www.splashnews.com
Pitt and Jolie go public for the first time on a motorcycle ride in Edmonton, Canada, on Sept. 25, 2005.Splash
NARITA, JAPAN: Hollywood stars Angelina Jolie (R) and Brad Pitt (L), accompanied by Jolie's children, arrive at Narita Airport in suburban Tokyo, 27 November 2005. The two stars are now here for the promotion of their movie "Mr. and Mrs. Smith", which will be screened in Japan from 03 December. AFP PHOTO / Yoshikazu TSUNO (Photo credit should read YOSHIKAZU TSUNO/AFP/Getty Images)
Jolie, Pitt and kids Maddox and Zahara Jolie-Pitt land at Narita Airport in Tokyo on Nov. 27, 2005.Getty
Mum-to-be Angelina Jolie has no plans of slowing down her hectic schedule. The 30-year-old actress, who has been filming her new movie 'The Good Shepherd' in the Dominican Republic, boarded a helicopter today with boyfriend Brad Pitt. The pair - who earlier in the week announced they are expecting a baby in the summer - traveled from the Caribbean island to the neighbouring nation of Haiti. In her role as a U.N. goodwill ambassador Jolie visited a school supported by Yele Haiti, a charity founded by Haitian-born 'Fugees' musician Wyclef Jean where they watched children dance and recite poetry. The pair traveled in a convoy through the capital of Port-au-Prince, protected by police and U.N. peacekeepers as crowds cheered them along the way. "You hear so much just about the danger and the fear and then you come here and you meet just an amazing people," said Jolie Wyclef Jean thanked the actors for their visit. "To have these people grace our country is a beautiful thing," he said. Picture by: Joseph Ulrick Colas / Image Nouvelle / Splash News Ref: SPL 130106 A Splash News and Pictures Los Angeles: 310-821-2666 New York: 212-619-2666 London: 207-107-2666 photodesk@splashnews.com www.splashnews.com
Pitt and a pregnant Jolie go on a U.N. goodwill trip to a school in Port-au-Prince, Haiti, on Jan. 13, 2006.Splash
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Brad Pitt, Angelina Jolie and their children Maddox and Zahara pictured at Roissy Airport in Paris, France. Ref: KCS 040306 N Splash News and Pictures Los Angeles: 310-821-2666 New York: 212-619-2666 London: 207-107-2666 photodesk@splashnews.com www.splashnews.com
The jet-setting Jolie-Pitt clan touches down in Roissy Airport in Paris on March 4, 2006.Splash
Hollywood couple Angelina Jolie (R) and Brad Pitt gives a press conference 07 June 2006, at a Swakopmund hotel. Hollywood's hottest couple became the proud parents of daughter Shiloh Nouvel Jolie-Pitt on May 27 in Namibia. AFP PHOTO/- (Photo credit should read /AFP/Getty Images)
Pitt and Jolie attend a press conference in a Swakopmund, Namibia, hotel on June 7, 2006.Getty
US actor Angelina Jolie (L) holds daughter Zahara as husband and actor Brad Pitt (C) carries son Maddox during a stroll on the seafront promenade at the historic Gateway of India, (R) outside their hotel in Mumbai, 12 November 2006. Jolie and Pitt are in India's financial hub - Mumbai to shoot for her film "A Mighty Heart", based on the life of the slain Wall Street Journal reporter Daniel Pearl in which Jolie portrays Marianne - wife of Daniel Pearl. (Photo credit should read STR/AFP/Getty Images)
Jolie and Pitt escort Maddox and Zahara around Mumbai, India, on Nov. 12, 2006.Getty
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MUMBAI, INDIA: US actress and UNHCR Ambassador Angelina Jolie (R) with son Maddox and Brad Pitt (3L) with daughter Zahara leave on a boat to the Elephanta Island from Gateway of India in Mumbai, 18 November 2006. Brad Pitt and Angelina Jolie, along with their children, took a break after the incident during which their bodyguards were arrested by Indian police on 17 November and then freed on bail following a scuffle with parents at a Mumbai Islamic school during a movie shoot. AFP PHOTO/Sebastian D'SOUZA (Photo credit should read SEBASTIAN D'SOUZA/AFP/Getty Images)
Pitt, Jolie, Maddox and Zahara Jolie-Pitt take a boat ride in Mumbai, India, on Nov. 18, 2006.Getty
Ho Chi Minh City, VIET NAM: (FILES) Hollywood movie stars Brad Pitt (C) and his partner Angelina Jolie ride on a motorcycle on a busy street in downtown Ho Chi Minh city, 23 November 2006. Jolie, the partner of fellow screen idol Brad Pitt, was expected to adopt a three-year-old Vietnamese boy 15 March 2007, according to the head of the Tam Binh orphanage, from where the child is. AFP PHOTO/FILES (Photo credit should read STR/AFP/Getty Images)
Pitt and Jolie ride motorcycles in Ho Chi Minh City, Vietnam, on Nov. 23, 2006.Getty
BEVERLY HILLS, CA - JANUARY 15: Actors Brad Pitt and Angelina Jolie arrive at the 64th Annual Golden Globe Awards at the Beverly Hilton on January 15, 2007 in Beverly Hills, California. (Photo by Frazer Harrison/Getty Images)
Pitt and Jolie arrive at the Golden Globes on Jan. 15, 2007 in Beverly Hills.Getty
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CANNES, FRANCE - MAY 24: Actors Brad Pitt and Angelina Jolie depart the premiere for the film 'Ocean's Thirteen' at the Palais des Festivals during the 60th International Cannes Film Festival on May 24, 2007 in Cannes, France. (Photo by Francois Durand/Getty Images)
Pitt and Jolie leave the "Ocean's Thirteen" premiere in Cannes on May 24, 2007.Getty
HOLLYWOOD - JUNE 05: Actress Angelina Jolie and actor Brad Pitt arrive to the Warner Bros. premiere of the film "Ocean's 13" at Grauman's Chinese Theatre on June 5, 2007 in Hollywood, California. (Photo by Kevin Winter/Getty Images)
Jolie supports Pitt at the premiere of "Ocean's Thirteen" in Hollywood on June 5, 2007.Getty
VENICE, ITALY - SEPTEMBER 02: Brad Pitt and Angelina Jolie attend the The Assassination of Jesse James by the Coward Robert Ford premiere on the Day 5 of the 64th Annual Venice Film Festival on September 2, 2007 in Venice, Italy. (Photo by MJ Kim/Getty Images)
Pitt and Jolie look as loved up as ever at the Venice Film Festival on Sept. 2, 2007.Getty
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LONDON - NOVEMBER 11: Brad Pitt and Angelina Jolie attend the Beowulf film premiere held at the Vue Leicester Square on November 11, 2007 in London, England. (Photo by Gareth Cattermole/Getty Images)
Pitt and Jolie get close at the "Beowulf" London premiere on Nov. 11, 2007.Getty
LOS ANGELES - JANUARY 27: Actors Angelina Jolie (L) and Brad Pitt arrive at the 14th annual Screen Actors Guild awards held at the Shrine Auditorium on January 27, 2008 in Los Angeles, California. (Photo by Frazer Harrison/Getty Images)
Jolie and Pitt are joyous at the Screen Actors Guild Awards on Jan. 27, 2008.Getty
Brad Pitt, who seems to be channeling his inner Robert Redford Spy Game impression, and his visibly pregnant partner Angelina Jolie, wave to the crowd as they leave the Independent Spirit Awards in Santa Monica, California. Ref: SPL19683 230208 Picture by: London Entertainment/ Splash News Splash News and Pictures Los Angeles: 310-821-2666 New York: 212-619-2666 London: 870-934-2666 photodesk@splashnews.com
Jolie and Pitt leave the Independent Spirit Awards on Feb. 23, 2008.Splash
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US actors Brad Pitt (L) and Angelina Jolie pose as they arrive to attend the screening of US directors John Stevenson and Mark Osborne's animated film 'Kung Fu Panda' at the 61st Cannes International Film Festival in Cannes, southern France, on May 15, 2008. The Cannes film festival on May 14, 2008 officially unrolled its red carpet with a star-studded ceremony kicking off the 12-day frenzy of movies, parties and deals. AFP PHOTO / Francois Guillot (Photo credit should read FRANCOIS GUILLOT/AFP/Getty Images)
Pitt and Jolie arrive at the "Kung Fu Panda" premiere at the Cannes Film Festival on May 15, 2008.Getty
US actors Angelina Jolie (L) and Brad Pitt pose as they arrive to attend the screening of US actor and director Clint Eastwood's film 'The Exchange' at the 61st Cannes International Film Festival on May 20, 2008 in Cannes, southern France. Clint Eastwood and Angelina Jolie drew warm applause at Cannes on May 20, 2008 for a wrenching drama based on a true story of a single mother in 1920s California whose son vanishes. AFP PHOTO / Anne-Christine Poujoulat (Photo credit should read ANNE-CHRISTINE POUJOULAT/AFP/Getty Images)
Pitt holds a pregnant Jolie at the Cannes Film Festival on May 20, 2008.Getty
WESTWOOD, CA - DECEMBER 08: Actress Angelina Jolie and actor Brad Pitt arrive at the premiere of Paramount's "The Curious Case Of Benjamin Button" held at Mann's Village Theatre on Decemeber 8, 2008 in Westwood, California. (Photo by Alberto E. Rodriguez/Getty Images)
Jolie and Pitt chuckle at the Los Angeles premiere of "The Curious Case of Benjamin Button" on Dec. 8, 2008.Getty
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SANTA MONICA, CA - JANUARY 08: Actress Angelina Jolie and actor Brad Pitt arrive at VH1's 14th Annual Critics' Choice Awards held at the Santa Monica Civic Auditorium on January 8, 2009 in Santa Monica, California. (Photo by Frazer Harrison/Getty Images for VH1)
Jolie and Pitt stay close at the Critics' Choice Awards in Santa Monica, Calif., on Jan. 8, 2009.Getty
BEVERLY HILTON, CA - JANUARY 11: Actors Brad Pitt and Angelina Jolie arrive at the 66th Annual Golden Globe Awards held at the Beverly Hilton Hotel on January 11, 2009 in Beverly Hills, California. (Photo by Frazer Harrison/Getty Images)
Pitt and Jolie shine at the Golden Globes on Jan. 11, 2009 in Beverly Hills.Getty
PARIS - JANUARY 22: Brad Pitt and Angelina Jolie arrive to attend "The Curious Case of Benjamin Button" Paris Premiere on January 22, 2009 at Gaumont Marignan in Paris (Photo by Pascal Le Segretain/Getty Images)
The couple coordinates at the Paris premiere of "The Curious Case of Benjamin Button" on Jan. 22, 2009.Getty
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LOS ANGELES, CA - FEBRUARY 22: Actors Angelina Jolie and Brad Pitt arrive at the 81st Annual Academy Awards held at Kodak Theatre on February 22, 2009 in Los Angeles, California. (Photo by Jason Merritt/Getty Images)
Jolie and Pitt laugh at the Academy Awards in Los Angeles on Feb. 22, 2009.
US actor Brad Pitt and actress Angelina Jolie arrive for the screening of the movie "Inglourious Basterds" directed by US Quentin Tarantino in competition at the 62nd Cannes Film Festival on May 20, 2009. AFP PHOTO / VALERY HACHE (Photo credit should read VALERY HACHE/AFP/Getty Images)
Pitt and Jolie pose at the Cannes Film Festival on May 20, 2009.Getty
Angelina Jolie and Brad Pitt take kids Maddox, Pax, Zahara and Shiloh to see Mary Poppins on Broadway. Pictured: Brad Pitt and Angelina Jolie with Zahara, Shiloh and Pax Jolie-Pitt Ref: SPL148738 030110 Picture by: Splash News Splash News and Pictures Los Angeles: 310-821-2666 New York: 212-619-2666 London: 870-934-2666 photodesk@splashnews.com
Pitt and Jolie take their kids to see "Mary Poppins" on Broadway on Jan. 3, 2010.Splash
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HOLLYWOOD - JULY 19: Actor Brad Pitt (L) and actress Angelina Jolie arrive at the premiere of Sony Pictures' "Salt" at Grauman's Chinese Theatre on July 19, 2010 in Hollywood, California. (Photo by Kevin Winter/Getty Images)
Jolie clutches Pitt at the Hollywood premiere of "Salt" on July 19, 2010.Getty
ROME, ITALY - DECEMBER 15: Brad Pitt and Angelina Jolie attend "The Tourist" premiere at The Space Cinema on December 15, 2010 in Rome, Italy. (Photo by Elisabetta Villa/Getty Images)
Pitt and Jolie attend the Rome premiere of "The Tourist" on Dec. 15, 2010.Getty
BEVERLY HILLS, CA - JANUARY 16: Actor Brad Pitt (L) and actress Angelina Jolie arrive at the 68th Annual Golden Globe Awards held at The Beverly Hilton hotel on January 16, 2011 in Beverly Hills, California. (Photo by Jason Merritt/Getty Images)
Pitt and Jolie arrive at the Golden Globes on Jan. 16, 2011 in Beverly Hills.Getty
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HOLLYWOOD, CA - MAY 22: Actors Angelina Jolie (L) and Brad Pitt arrive at DreamWorks Animation's "Kung Fu Panda 2" Los Angeles Premiere held at Grauman's Chinese Theatre on May 22, 2011 in Hollywood, California. (Photo by Alberto E. Rodriguez/Getty Images)
Jolie and Pitt laugh at the Los Angeles premiere of "Kung Fu Panda 2" on May 22, 2011.Getty
US actors Brad Pitt and Angelina Jolie pose on the red carpet before the screening of "The Tree of Life" presented in competition at the 64th Cannes Film Festival on May 16, 2011 in Cannes. AFP PHOTO / VALERY HACHE (Photo credit should read VALERY HACHE/AFP/Getty Images)
Pitt holds Jolie close at the Cannes Film Festival on May 16, 2011.Getty
Brangelina and the kids, Maddox, Pax, Zahara, Shiloh, Vivienne and Knox, landed in Japan at Tokyo's Haneda International Airport. Hundreds of screaming fans waited for hours to catch a glimpse of the Hollywood stars and were delighted to see the whole family arrive. Brad is in Japan to promote his new film, 'Moneyball.' Pictured: Brad Pitt, Angelina Jolie, Maddox Jolie-Pitt, Pax Jolie-Pitt, Zahara Jolie-Pitt, Shiloh Jolie-Pitt and Vivienne Jolie-Pitt Ref: SPL320826 071111 Picture by: Scott Larson / / Splash News Splash News and Pictures Los Angeles: 310-821-2666 New York: 212-619-2666 London: 870-934-2666 photodesk@splashnews.com
Pitt, Jolie and their brood arrive in Haneda Airport in Tokyo on Nov. 7, 2011.Splash
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Hollywood stars Angelina Jolie (C) and Brad Pitt (2nd-R) get off a plane with their children at the Con Son Airport on Con Dao island, offshore of Ba Ria Vung Tau province in Vietnam on November 11, 2011. Jolie is in Vietnam for her first known visit since adopting an orphan from the country four years ago. Jolie and Pitt landed in the southern metropolis of Ho Chi Minh City with their adopted son Pax Thien and their five other children, VNExpress online newspaper reported. AFP PHOTO / VNExpress (Photo credit should read duc manh/AFP/Getty Images)
Jolie, Pitt and the tykes land in Con Dao, Vietnam, on Nov. 11, 2011.Getty
NEW YORK, NY - DECEMBER 05: Angelina Jolie and Brad Pitt pose with Bill Ptt and Jane Pitt at the after party for the premiere of "In the Land of Blood and Honey" at the The Standard Hotel Rooftop on December 5, 2011 in New York City. (Photo by Stephen Lovekin/Getty Images)
Jolie poses with Pitt and his parents at the New York premiere of "In the Land of Blood and Honey" on Dec. 5, 2011.Getty
PALM SPRINGS, CA - JANUARY 07: Actors Angelina Jolie and Brad Pitt arrive at the 2012 Palm Springs International Film Festival Awards Gala at Palm Springs Convention Center on January 7, 2012 in Palm Springs, California. (Photo by Frazer Harrison/Getty Images)
Pitt beams at Jolie at the Palm Springs International Film Festival on Jan. 7, 2012.Getty
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BEVERLY HILLS, CA - JANUARY 15: (R-L) Actors Brad Pitt and Angelina Jolie arrive at the 69th Annual Golden Globe Awards held at the Beverly Hilton Hotel on January 15, 2012 in Beverly Hills, California. (Photo by Frazer Harrison/Getty Images)
Jolie and Pitt arrive at the Golden Globes on Jan. 15, 2012 in Beverly Hills.Getty
BERLIN, GERMANY - FEBRUARY 11: Brad Pitt and director Angelina Jolie attend the "In The Land Of Blood And Honey" Premiere during day three of the 62nd Berlin International Film Festival at the Haus der Berliner Festspiele on February 11, 2012 in Berlin, Germany. (Photo by Pascal Le Segretain/Getty Images)
Pitt and Jolie joke at the Berlin premiere of "In the Land of Blood and Honey" on Feb. 11, 2012.Getty
BERLIN, GERMANY - FEBRUARY 13: Angelina Jolie and Brad Pitt attend the Cinema for Peace Gala ceremony at the Konzerthaus Am Gendarmenmarkt during day five of the 62nd Berlin International Film Festival on February 13, 2012 in Berlin, Germany. (Photo by Pascal Le Segretain/Getty Images for Cinema for Peace)
Pitt keeps his arm around his lady at the Cinema for Peace Gala on Feb. 13, 2012 in Berlin.Getty
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HOLLYWOOD, CA - FEBRUARY 26: Actor Brad Pitt (L) and actress Angelina Jolie arrive at the 84th Annual Academy Awards held at the Hollywood & Highland Center on February 26, 2012 in Hollywood, California. (Photo by Jason Merritt/Getty Images)
Pitt, Jolie and that infamous leg arrive at the Oscars on Feb. 26, 2012.Getty
LONDON, ENGLAND - JUNE 02: Angelina Jolie & Brad Pitt attends the World Premiere of 'World War Z' at The Empire Cinema on June 2, 2013 in London, England. (Photo by Tim P. Whitby/Getty Images)
Jolie and Pitt attend the London premiere of "World War Z" on June 2, 2013.Getty
BERLIN, GERMANY - JUNE 04: Actors Angelina Jolie and Brad Pitt attend 'WORLD WAR Z' Germany Premiere at Sony Centre on June 4, 2013 in Berlin, Germany. (Photo by Andreas Rentz/Getty Images for Paramount Pictures)
Jolie supports Pitt at the Berlin premiere of "World War Z" on June 4, 2013.Getty
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HOLLYWOOD, CA - NOVEMBER 16: (L-R) Maddox Jolie-Pitt, Actress Angelina Jolie and actor Brad Pitt arrive at the Academy of Motion Picture Arts and Sciences' Governors Awards at The Ray Dolby Ballroom at Hollywood & Highland Center on November 16, 2013 in Hollywood, California. (Photo by Frederick M. Brown/Getty Images)
Jolie and Pitt have a special guest at the Governors Awards on Nov. 16, 2013 in Hollywood: son Maddox.Getty
LONDON, ENGLAND - FEBRUARY 16: Actors Angelina Jolie and Brad Pitt attend the EE British Academy Film Awards 2014 at The Royal Opera House on February 16, 2014 in London, England. (Photo by Chris Jackson/Getty Images)
Jolie and Pitt attend the British Academy Film Awards on Feb. 16 in London.Getty
HOLLYWOOD, CA - MARCH 02: Actors Brad Pitt (L) and Angelina Jolie attend the Oscars held at Hollywood & Highland Center on March 2, 2014 in Hollywood, California. (Photo by Jason Merritt/Getty Images)
Jolie and Pitt attend the Academy Awards on March 2 in Hollywood.Getty
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LONDON, ENGLAND - MAY 08: Brad Pitt and Angelina Jolie attend a private reception as costumes and props from Disney's "Maleficent" are exhibited in support of Great Ormond Street Hospital at Kensington Palace on May 8, 2014 in London, England. (Photo by Anthony Harvey/Getty Images)
Pitt and Jolie beam at one another at the "Maleficent" London premiere on May 8.Getty
Angelina Jolie and Brad Pitt arrive for the world premiere of Disney's "Maleficent," May 28, 2014, at El Capitan Theatre in Hollywood, California. AFP PHOTO / ROBYN BECK (Photo credit should read ROBYN BECK/AFP/Getty Images)
Pitt and Jolie share a smile at the Hollywood premiere of "Maleficent" on May 28.Getty
Angelina Jolie and Brad Pitt take all their children, Shiloh, Maddox, Pax, Vivienne, Knox and Zahara out for a walk to pick up candy in New Orleans, LA. Pictured: Brad Pitt, Angelina Jolie, Maddox Jolie-Pitt, Pax Thien Jolie-Pitt, Zahara Jolie-Pitt, Shiloh Jolie-Pitt, Knox Leon Jolie-Pitt, Vivienne Marcheline Jolie-Pitt Ref: SPL258866 200311 Picture by: StClair/Massie/Splash News Splash News and Pictures Los Angeles: 310-821-2666 New York: 212-619-2666 London: 870-934-2666 photodesk@splashnews.com
Jolie, Pitt and their brood go for a stroll in the New Orleans French Quarter on March 20, 2011.Splash
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Jolie and Pitt attend the Global Summit To End Sexual Violence In Conflict in London on June 13, 2014.Getty Images
Angelina Jolie and Brad Pitt arrived at LAX from London with children Maddox and Zahara. Maddox was accompanied by his girlfriend. Pictured: Angelina Jolie, Brad Pitt and Sahara Jolie-Pitt Ref: SPL780702 140614 Picture by: MAP / Splash News Splash News and Pictures Los Angeles: 310-821-2666 New York: 212-619-2666 London: 870-934-2666 photodesk@splashnews.com
Jolie and Pitt arrive at LAX with Zahara on June 14.Splash
The pair attend the 15th Annual AFI Awards Luncheon on Jan. 9, 2015 in Beverly Hills, California. Getty Images
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The duo attend a screening of "By the Sea" on Nov. 3, 2015 in New York City.Getty Images
Pitt, Jolie and Anna Wintour chat at the WSJ. Magazine 2015 Innovator Awards at the Museum of Modern Art on Nov. 4, 2015. Getty Images
Jolie and Pitt attend the premiere of "By the Sea" during the AFI Fest on Nov. 5, 2015. Getty Images
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Jolie and Pitt attend a party for "By the Sea" on Nov. 5, 2015.Getty Images
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Jolie’s manager, Geyer Kosinski, said Tuesday, “Angelina will always do what’s in the best interest to protect her children.

“She appreciates everyone’s understanding of their need for privacy at this time,’’ he told E! News.

Pitt added in a statement to People magazine, “I am very saddened by this, but what matters most now is the well-being of our kids.

“I kindly ask the press to give them the space they deserve during this challenging time.”

In addition to her husband’s alleged affair, Jolie, 41, was sick and tired of constantly sparring over their lifestyle, another source told The Post.

She has increasingly wanted to quit Hollywood in favor of devoting herself full-time to traveling the globe for her humanitarian work, while Pitt prefers Tinseltown and its parties, the source said.

Jolie spoke before the United Nations in Manhattan just this past Friday to ask them to help millions of Syrian refugees.

“The older she gets, the more serious she becomes, and she is sick of the Hollywood thing,’’ the second source said.

“He wants to make movies. She doesn’t. It’s a fundamental difference. It’s how you live your life.’’

Making matters worse, Pitt is closer to Jolie’s famous actor dad, Jon Voight, than she is, the source said.

“Jon’s a Hollywood guy, and she’s been estranged. Brad hangs out with her father more than she does,’’ the source said.

Another source told TMZ that Jolie believes that her hubby’s drinking and pot-smoking is affecting their kids.

Add to that his “anger problem,” and the mom of six said enough is enough, the source told the website.

Jolie filed for divorce Monday, citing “irreconcilable differences.”

She is seeking physical custody of the couple’s kids, TMZ said. She doesn’t want Pitt to have joint physical custody, just joint legal custody. He would get visitation, according to her filing.

Jolie is not seeking spousal support, the website said.

Brangelina’s French chateau, Miraval — where the couple married in August 2014 — has been quietly on the market for a few months, and locals were told they were selling it because they are breaking up, a source told The Post.

Jolie has hired top gun Laura Wasser as her lawyer.

The court documents list the couple’s date of separation as Sept. 15, 2016.

The couple have been together since 2004.

A rep for Cotillard did not immediately get back to The Post.