Mario Testino exclusively for Vanity Fair
She has won an Oscar and regularly conquers the box office — so how hard could winning an election be?

Globe-trotting Hollywood do-gooder Angelina Jolie hints in a new interview that she’s ready to enter politics.

“When you work as a humanitarian, you are conscious that politics have to be considered. Because if you really want to make an extreme change, then you have a responsibility,” Jolie, 39, tells Vanity Fair’s December issue.

“I honestly don’t know in what role I would be more useful — I am conscious of what I do for a living, and that [could] make it less possible,” said Jolie, director and a special envoy for the UN High Commissioner for Refugees.

Pushed further, she admitted, “I am open” to pursing politics.

Jolie — who directed the upcoming film “Unbroken,” about Olympian-turned-war hero Louis Zamperini — also dished on tying the knot with Brad Pitt, her partner of 10 years.

“It does feel different,” she said. “It feels nice to be husband and wife.”

The pair got hitched in the South of France in August, and Jolie said their six children lent a hand.

“There was no cake, so Pax made a cake,” she said, referring to their second-oldest son.

“The kids made little pillows for the rings, and Knox practiced [being a ringbearer] with an acorn that kept falling off the pillow. Brad’s mom went and picked some flowers and tied them up.”

She said their kids wrote her and Pitt’s vows.

“They did not expect us never to fight, but they made us promise to always say ‘sorry’ if we do. So they said, ‘Do you?’ and we said, ‘We do!’ ” Jolie said.

She noted both she and Pitt worked on war movies at the same time recently, with Pitt on the World War II tank thriller “Fury” and her on “In the Land of Blood and Honey.”

They sent each other notes in the mail to replicate how World War II GIs received letters from loved ones back home, she said.

She broke down in tears discussing the true story behind “Unbroken,” due out next month, and Zamperini’s incredible tale of survival.

Zamperini, who ran in the 1936 Berlin Games, flew in the Air Force and was shot down over the Pacific. He floated at sea for 47 days before he was captured and sent to a Japanese POW camp.

“It was an extremely emotional experience, to watch someone watching their own life … someone so physically strong … and they are at the stage where their body is giving up,” she said.

Jolie donned a Max Mara blouse, Halston Heritage pants and a Burberry Prorsum dress for the VF shoot.