Katherine Heigl is trying for a career boost by jumping Hollywood agencies.

She moved to WME from CAA this week, and sources said the catalyst was her mom and manager, Nancy.

The “Grey’s Anatomy” star has appeared in a long string of box-office duds, including “Killers” with Ashton Kutcher, and “One for the Money.”

A source said, “Nancy thinks Katherine should be like Julia Roberts or Meryl Streep.”

Heigl’s moving to NBC’s CIA pilot “State of Affairs.”