Larry David has gone from home-wrecked to home-wrecker with his new girlfriend, Amy Landecker, who was married when they met.

The “Curb Your Enthusiasm” creator, whose ex-wife, Laurie, left him in 2007, has moved on with the lovely Landecker, 41, who was married when he wooed her on the set of the HBO show in August 2010. They met when they filmed the episode titled “The Bi-sexual” which aired on Aug. 21.

Landecker, who starred in “A Serious Man,” appeared on the episode as bisexual “Jane,” who was pursued by both Larry and his rival, Rosie O’Donnell.

Sources tell us there were “sparks on the set” between Larry and Landecker, who was wed for six years to journalist Jackson Lynch with whom she has a daughter. The couple filed for a divorce in March, but Landecker has been seen on Larry’s arm in New York and LA since February. The two are still in the midst of finalizing the divorce.

Larry recently opened up about his split with environmental activist Laurie after 14 years of marriage: “Well, she thought that it would be nice to have sex with someone she liked. She wanted to try that. And I said it’s not a good idea.” Laurie reportedly left Larry for Martha’s Vineyard contractor Bart Thorpe.

Landecker’s rep told us it is “unequivocally not true” that David was the cause of the break-up of Lynch and Landecker’s marriage.

But Lynch told us David and Landecker were in a relationship before he filed for a divorce. “This is obviously a sad set of circumstances for our family,” Lynch said. “As far we are concerned it’s a private family matter.”

He added, “If you want more details about their relationship you should reach out to Larry.”

Larry told us through his rep, “For what it’s worth, the only marriage I’ve ever broken up is my own.”