Madonna opens her first national tour in 1985 in Seattle.
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Madonna and then-hubby Sean Penn chat with photographers in 1986.
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Ron Silver, left, Madonna and Joe Mantegna take their curtain call after the opening performance of Madonna’s Broadway debut of David Mamet’s “Speed-the-Plow” in 1988.
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Madonna performs during her Blond Ambition tour in 1990.
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Madonna leaves the screening of her movie “Truth or Dare” in 1991.
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Madonna and her father, Tony Ciccone, laugh as they talk with Arsenio Hall during taping of Hall’s talk show 1992.
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David Letterman joins Madonna onstage before she presented an award at the 1994 MTV Video Music Awards.
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In 1995, Madonna starred as Eva Peron in “Evita”.
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Madonna performs in San Remo in 1998.
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Madonna poses with her MTV Award in 1998.
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Madonna waves to the crowd as Guy Ritchie holds their son Rocco after his baptism in 2000.
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Madonna performs in Milan in 2001.
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Madonna takes the stage for her Drowned World Tour in 2001.
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Madonna waits in line to meet Britain’s Queen Elizabeth II in 2002.
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Madonna laughs as she sits with Jeremy Zorek, 18 months, at a book signing of her new children’s book “The English Roses” in 2003.
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Britney Spears and Madonna kiss during the opening performance of the MTV Video Music Awards in 2003.
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Madonna performs during a concert of her Re-Invention World Tour in 2004.
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Madonna wears a diamond encrusted “E” necklace as she visits the tomb of Kabbalist Rabbi Yehuda Ashlag, a Jewish mystic in 2004.
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Madonna performs during the German TV show ‘Wetten dass, …?’ (‘Bet that …’) in 2005.
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Madonna and daughter Lourdes arrive at the world premiere of “Harry Potter and the Goblet of Fire” in 2005.
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Madonna poses as she attends the 2005 MTV Europe Music Awards.
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Madonna appears backstage at the 48th Annual Grammy Awards in 2006.
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Madonna performs during her Confession concert in Moscow in 2006.
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Another ‘Confession.’
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Madonna sits with her daughter Lourdes, 9, left, son Rocco, 6, right and David Banda, 13-months, who she adopt in 2007.
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Madonna holds her adopted son David Banda in her arms as her daughter Lourdes, looks on, at the Home of Hope orphanage in Mchinji, Malawi in 2007.
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Madonna and her husband, director Guy Ritchie, arrive at the Vanity Fair Party in 2007.
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Madonna performs on stage during the British leg of the Live Earth concerts in 2007.
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Guy Ritchie and Madonna attend a special screening of “Revolver” in 2007.
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Madonna is inducted into the Rock and Roll Hall of Fame in April, 2008.
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Madonna attends the premiere of her film “I Am Because We Are” in 2008.
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Madonna and Guy Ritchie pose during the 61st Cannes Film Festival in 2008.
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Madonna arrives for the 2008 amfAR Cinema Against AIDS benefit.
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Madonna visits the slums of Mumbai city, India in 2008.
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Madonna shows off her assets while on the stage of her “Stickey and Sweet” tour.
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Madonna stikes a pose on stage.
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Madonna holds her adopted son David on her lap during a visit to Malawi. David’s natural-born father sits with them. Madonna returned to the country in an attempt to adopt another child but a court denied her request.
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Madonna, never afraid of fashion, wore a daring outfit to the Met’s Costume Institute Gala.
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Madonna leaves the gala with her latest boy toy, Jesus Luz.
